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Corn & Apoptosis

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Not to incise Corn unnecessarily
Corn is caused due to Friction (Resistance, Rubbing, Roughness) of unfit (out of shape, in poor condition, ailing) foot wear, Pen (writing implement) and other consistent occupational (work-related) reason in susceptible individuals with delicate skin. Being caused by persistent ongoing unnoticed injury corns when incised lead to severe aggravation.
Synonyms: Corn, Hard skin, Callus, Lump, Bump, Protuberance, Bulge, Knob etc.

Homoeopathy and Management of Corn
First of all we have to remove the exciting and maintaining cause i.e. Friction, by changing foot wear and writing implement and eliminate other work related causes. Then eradicate the fundamental cause i.e. individual susceptibility by means of similar deep acting Homeopathic Medicine.

Modus operandii of Homoeopathic Medicine in case of Corns
Tumor Necrosing Factor (TNF) is responsible for restricting untoward growth of the living cells. Deficiency of TNF or insensitivity of body parts of living being with untoward growth of the living cells to TNF influence results in lump development. Dynamic Homeopathic remedy resets the harmony of life force and in turn uniformity of TNF throughout the living being leading to regression of corn.

A new study suggests that commonly used Homoeopathic Medicines have tumor-fighting properties that prevent or slow the growth of tumors. The study found that Homoeopathic Medicine caused tumor cells to die through a process called apoptosis – the body’s normal method of disposing of damaged, unwanted or unneeded cells. This process often is faulty in cancer cells.
Apoptosis is a process of deliberate life relinquishment by a cell in a multi cellular organism. It is one of the main types of programmed cell death (PCD), and involves an orchestrated series of biochemical events leading to a characteristic cell morphology and death. The apoptotic process is executed in such a way as to safely dispose of cell corpses and fragments.
In contrast to necrosis, which is a form of traumatic cell death that results from acute cellular injury, apoptosis is carried out in an orderly process that generally confers advantages during an organism's life cycle. For example, the differentiation of fingers and toes in a developing human embryo requires cells between the fingers to initiate apoptosis so that the digits can separate. Between 50 billion and 70 billion cells die each day due to apoptosis in the average human adult. For an average child between the ages of 8 to 14, approximately 20 billion to 30 billion cells die a day. In a year, this amounts to the proliferation and subsequent destruction of a mass of cells equal to an individual's body weight.
TNF is a cytokine produced mainly by activated macrophages, and is the major extrinsic mediator of apoptosis. Most cells in the human body have two receptors for TNF: TNF-R1 and TNF-R2.
Apoptosis can occur when a cell is damaged beyond repair.
Homeopathic remedy stimulates Cytotoxic T-cells able to directly induce apoptosis in cells by opening up pores in the target's membrane and releasing chemicals which bypass the normal apoptotic pathway. The pores are created by the action of secreted perforin, and the granules contain granzyme B, a serine protease which activates a variety of events by cleaving aspartate residues.
Although many pathways and signals lead to apoptosis, there is only one mechanism which actually causes the death of the cell in this process; after the appropriate Homeopathic stimulus has been received by the cell and the necessary controls exerted, a cell will undergo the organized degradation of cellular organelles by activated proteolytic events. A cell undergoing apoptosis shows a characteristic morphology that can be observed with a microscope.
Dying cells that undergo the final stages of apoptosis display phagocytotic molecules, such as phosphatidylserine, on their cell surface. These molecules mark the cell for phagocytosis by cells possessing the appropriate receptors, such as macrophages. Upon recognition, the phagocyte reorganizes its cytoskeleton for engulfment of the cell. The removal of dying cells by phagocytes occurs in an orderly manner without eliciting an inflammatory response.
Homeostasis is achieved when the rate of mitosis (cell division) in the tissue is balanced by cell death. If this equilibrium is disturbed, one of two potentially fatal disorders occurs:
The cells are dividing faster than they die, effectively developing a tumor.
The cells are dividing slower than they die, which results in a disorder of cell loss.





   
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